Over the years, technology has been growing fast promoting advancements in various fields. Medical field is one of the industries that is being flooded with innovative advancements to improve the quality of living of the people. Among the many branches of medicine, scientists are now intrigued to research the efficiency of their infertility treatments. It’s time to know what you don’t. Here are some of the latest treatments and research concerning infertility in today’s world.
1) Follicle-Stimulating Hormones (FSH)
This is a hormone released by the pituitary gland into the bloodstream that regulates the functions of the ovaries and testes. A lack of FSH can lead to infertility or subfertility in both men and women. In women, the hormone levels drop as they reach the end of their menstrual cycles which will be sensed by the nerve cells in the hypothalamus. The nerve cells then produce more gonadotrophin-releasing hormone that stimulates the pituitary gland to produce more FSH and luteinising hormones (LH) to be released into the bloodstream. A rise in FSH stimulates the growth of follicle in the ovary. As the number of follicle increases, more oestrogen is produced, elevating the LH and FSH that stimulates the release of eggs from the mature follicles, a process called ovulation. Whereas in men, FSH is produced by the testes, through the circulating levels of testosterone and inhibin. The FSHregulates testosterone levels where as this level rises, the gonadotrophin-releasing hormones and FSH are consequently decreased.
It has been said that too much of FSH in a woman’s body reduces the chances of woman to get pregnant during the IVF. The current research is focused on identifying the optimal level of FSH to increase the likelihood of women getting pregnant and delivering a live baby.
2) DNA Fragmentation Index
DNA Fragmentation Index or DFI is a method where the quality of the sperms before the treatments such as in-vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI). The research team in Sweden came up with DFI, which is used to look for any chromosomal breaks in the sperm that can be the cause of infertility. It has been deemed important for the sperms to be analysed thoroughly for a successful fertilization and promote a normal development of the embryo. Also, if there is a severe chromosomal break in the sperms, it may lead to the male’s subfertility and result in a failure in the IVF treatment.
3) Intravaginal Culture (IVC)
Intravaginal culture (IVC) or also known as the intravaginal culture of oocytes (INVO) is an assisted reproduction procedure where the fertilization of the oocyte and the development of early embryo are carried out, that too within a gas permeable air-free place device. This device is used by placing it into the maternal vaginal cavity for the purpose of incubation. In a similar context, a US company has also introduced the INVOcell, that has the similar yet better function than an incubator. With INVOcell, a woman is able to carry the embryo with her in the vagina. Initially, the sperm and egg are mixed in the lab, placed in the INVOcell, a tiny capsule which will be inserted into the woman’s vagina. The embryos will be removed after five days from the capsule and one or more will then be implanted into the uterus, following the usual procedure.
As of now, the INVOcell has been approved for infertility treatment in Canada and the US, that too in selected clinics. This is a safer and potential way to promote fertility as the capsule uses the woman’s body temperature to regulate the embryo’s environment.
The research doesn’t stop here. Scientists are still trying to improve the ways to treat infertility for higher rate of success in pregnancies.
Stay tuned with us for more updates on treatments for infertility.